I deeply resonate with what you are saying and know others (myself included) processing similar experience. Might it be a part of yourself that you lost long time ago, perhaps a connection to yourself that is not there anymore? There is nothing other than the original that can fill that space. To heal it naturally would be to hold space for the emptiness and allow the original energy to return, if it's right and proper. Filling it with anything external will possibly bring about a sense of unfulfillment, so why not keep it open and clear? 

Perhaps the sense of loss has brought you a unique wisdom and doesn't need to be reversed? With the reversal you'd loose that invaluable insight that you have now. Perhaps it is time to allow for more integration and reconnection to the fullness of who you are, if that is your choice. 

With love.